every Wednesday, 12:00-13:00, Pathologie-HS (Müllerstraße 44) Bernhard Radlinger (Kaser Lab) Empagliflozin protects from diet-induced obesity, insulin resistance and steatosis in mice Julia Hofmann (Schneeberger Lab) Mitochondrial respiration during normothermic machine perfusion of the liver predicts clinical outcome after transplantation

Andreas Villunger: Cell death 08:15-10:00 a.m. Location: Seminar room, ground floor, Müllerstraße 44 course documents: Charles L. Evavold, Iva Hafner-Bratkovič, Pascal Devant, ..., Arlene H. Sharpe, Jay R. Thiagarajah, Jonathan C. Kagan: Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway >>>Link<<< Galluzzi et al. CDD, 2018: Cell Death >>>download PDF<<<

Verena Labi: DNA methylation 08:15-10:00 a.m. Location: Seminar room, ground floor, Müllerstraße 44 course documents: Mamta Tahiliani, Kian Peng Koh, Yinghua Shen, William A. Pastor, Hozefa Bandukwala, Yevgeny Brudno, Suneet Agarwal, Lakshminarayan M. Iyer, David R. Liu, L. Aravind, Anjana Rao: Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1 >>>download PDF<<<

Oliver Schmidt: Cellular degradation pathways 08:15-10:00 a.m. Location: Seminar room, ground floor, Müllerstraße 44 course documents: Linhao ruan, chuankai Zhou, Erli Jin, andrei Kucharavy, Ying Zhang, Zhihui Wen, Laurence Florens & rong Li: Cytosolic proteostasis through importing of misfolded proteins into mitochondria >>>download PDF<<<

every Wednesday, 12:00-13:00, Pathologie-HS (Müllerstraße 44) Markus Ausserhofer (Finotello Lab) Computational prediction of non-canonical neoantigens to advance cancer immunotherapy

Michael Kullmann: Kinases and Phophatases in cellular homeostasis and diseases 08:15-10:00 a.m. Location: Seminar room, ground floor, Müllerstraße 44 course documents: Ken Morita, Shuning He, Radoslaw P. Nowak, ..., Nathanael S. Gray, Eric S. Fischer, A. Thomas Look: Allosteric Activators of Protein Phosphatase 2A Display Broad Antitumor Activity Mediated by Dephosphorylation of MYBL2 >>>download PDF<<<

Theresia Dunzendorfer-Matt: Signaling in Cancer: drug discovery 08:15-10:00 a.m. Location: Seminar room, ground floor, Müllerstraße 44 course documents: Matthew R. Janes, Jingchuan Zhang, Lian-Sheng Li, ..., Matthew P. Patricelli, Pingda Ren, Yi Liu: Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor >>>download PDF<<<

Markus Keller: Lipid metabolism 08:15-10:00 a.m. Location: Seminar room, ground floor, Müllerstraße 44 course documents:

every Wednesday, 12:00-13:00, Pathologie-HS (Müllerstraße 44) Raphael Gronauer (Hackl Lab) Integrative multi-omics analyzes to delineate the cancer immunome and therapeutic vulnerability affected by deficient DNA repair mechanisms Michael Jäger (Wilflingseder Lab) The role of complement in metabolic reprogramming of dendritic cells

Judith Hagenbuchner: Changes in metabolic pathways 08:15-10:00 a.m. Location: Seminar room, ground floor, Müllerstraße 44 course documents: Richard Burt, Aditi Dey, Sarah Aref, Melanie Aguiar, Ayse Akarca, Katharine Bailey, William Day, Steven Hooper, Amy Kirkwood, Kristina Kirschner, Soo-Wah Lee, Cristina Lo Celso, Jiten Manji, Marc R. Mansour, Teresa Marafioti, Rachel J. Mitchell, Robert C. Muirhead,…

every Wednesday, 12:00-13:00, Pathologie-HS (Müllerstraße 44) Vincent Braun (Villunger Lab) Evaluating the PIDDosome in promoting p53 induced tumor suppression Leo Pölzl (Holfeld Lab) Make it right: Reverse cardiac remodeling.